Editing the immune system
نویسندگان
چکیده
منابع مشابه
The new genomic editing system (CRISPR)
Over the past decades, progression in genetic element manipulation, and consequently, the treatment of diseases has been remarkable. It is worth noting that these genetic manipulations perform at different levels, including DNA and RNA. The earlier genomic editing techniques, including MN, ZFN , TALEN , performing their functions by creating double-stranded breaks (DSBs), and after breakage, th...
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Background: This study evaluated the effects of the maternal immune system stimulation or suppression during the pregnancy on the development of the neonate’s immune system.Methods: A total of 20 female rats were divided into four groups. The groups were treated using Leishmania major, Salmonella typhimurium, Tacrolimus, and sterilized normal saline. The animals were mated after 3-time tr...
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تداوم سلامتی انسان با سیستم ایمنی بدن مرتبط است. این سیستم از بافتهای متنوع، سلولها و عواملی تشکیل شده است که از بدن در مقابل آنتی ژنهای مضر و پاتوژنها حفاظت می کند. سلولهای ایمنی در زمان وجود عفونت جهت محدود کردن ضایعات سلولی و بافتی، تجمع می یابند. یک شبکه نظارت متشکل از سلولهای ایمنی در تشخیص سلولهای غیر طبیعی عمل می کنند. توانایی بدن در محافظت از خود در برابر عوامل خارجی، بخصوص باکتریها، و...
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Polynucleotide DNA and RNA editing enzymes alter nucleic acid sequences and can thereby modify encoded informational content. Two major families of polynucleotide editing enzymes, the AID/APOBEC cytidine deaminases (which catalyze the deamination of cytidine to uridine) and the adenosine deaminases acting on RNA (ADARs, which catalyze the deamination of adenosine to inosine), function in a vari...
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ژورنال
عنوان ژورنال: Genome Biology
سال: 2001
ISSN: 1465-6906
DOI: 10.1186/gb-spotlight-20010223-02